Primary research work

33764464
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2021-03 Mutagenic mechanism of cancer-associated DNA polymerase ε alleles
Mareike Herzog, Elisa Alonso-Perez, Israel Salguero, Jonas Warringer, David J. Adams, Stephen P. Jackson and Fabio Puddu
BioRxiv DOI:10.1101/2020.09.04.270124 September 2020
Nucleic Acids Research, in press, DOI:10.1093/nar/gkab160
GoogleScholar 11
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2019-09 Genome architecture and stability in the Saccharomyces cerevisiae knockout collection
Fabio Puddu, Mareike Herzog, Alexandra Selivanova, Siyue Wang, Jin Zhu, Shir Klein-Lavi, Molly Gordon, Roi Meirman,  Gonzalo Millan-Zambrano, Iñigo Ayestaran, Israel Salguero, Roded Sharan, Rong Li, Martin Kupiec, and Stephen P. Jackson
Nature,573(416–420) DOI:10.1038/s41586-019-1549-9
GoogleScholar 69
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2018-04 Detection of functional protein domains by unbiased genome-wide forward genetic screening
Mareike Herzog*, Fabio Puddu*, Julia Coates, Nicola Geisler, Josep V. Forment, and Stephen P. Jackson.
BioRxiv, October 12, 2017;
Scientific Reports, 8.DOI:10.1101/198416
GoogleScholar 12
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2017-03 Chromatin determinants impart camptothecin hypersensitivity. 
Fabio Puddu, Israel Salguero, Mareike Herzog, Nicola J. Geisler, Vincenzo Costanzo, and Stephen P. Jackson.
EMBO Reports, 2017, DOI:10.15252/embr.201643560
GoogleScholar 13
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2015-05 Synthetic viability genomic screening defines Sae2 function in DNA repair.
Fabio Puddu*, Tobias Oelschlaegel*, Ilaria Guerini, Nicola J Geisler, Hengyao Niu, Mareike Herzog, Israel Salguero, Bernardo Ochoa-Montaño, Emmanuelle Viré, Patrick Sung, David J Adams, Thomas M Keane and Stephen P Jackson.
EMBO Journal, 2015, DOI:10.15252/embj.201590973
GoogleScholar 50
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2011-03 Sensing of Replication Stress and Mec1 Activation Act through Two Independent Pathways Involving the 9-1-1 Complex and DNA Polymerase ?.
Fabio Puddu, Gabriele Piergiovanni, Paolo Plevani, and Marco Muzi-Falconi.
PLoS Genetics, 2011 DOI:10.1371/journal.pgen.1002022
GoogleScholar 60
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2008-08 Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.
Fabio Puddu*, Magda Granata*, Lisa Di Nola, Alessia Balestrini, Gabriele Piergiovanni, Federico Lazzaro, Michele Giannattasio, Paolo Plevani, and Marco Muzi-Falconi
Molecular and Cellular Biology, 2008 DOI:10.1128/mcb.00330-08
GoogleScholar 147
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Collaborations

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2020-09 Trajectory of mutational signatures in yeast mutators
Sophie Loeillet, Mareike Herzog, Fabio Puddu, Patricia Legoix, Sylvain Baulande, Stephen P. Jackson and Alain Nicolas
Proceedings of the National Academy of Sciences, 117 (40) 24947-24956; DOI:10.1073/pnas.2011332117
  GoogleScholar 27
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2018-11 Phosphorylation of histone H4-T80 triggers DNA damage checkpoint recovery
Gonzalo Millan-Zambrano*, Helena Santos-Rosa*, Fabio Puddu, Stephen P. Jackson and Tony Kouzarides
Molecular Cell, 72(4). DOI: j.molcel.2018.09.023
GoogleScholar 28
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2010-10 Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.
Michele Giannattasio, Cindy Follower, Hélène Tourrière, Fabio Puddu, Federico Lazzaro, Philippe Pasero, Massimo Lopes, Paolo Plevani, and Marco Muzi-Falconi.
Molecular Cell, 2010, DOI:10.1016/j.molcel.2010.09.004
GoogleScholar 123
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2010-08 Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity.
Magda Granata, Federico Lazzaro, Daniele Novarina, Davide Panigada, Fabio Puddu, Carla M Abreu, Ramesh Kumar, Muriel Grenon, Noel F Lowndes, Paolo Plevani, and Marco Muzi-Falconi
PLoS Genetics, 2010, DOI:10.1371/journal.pgen.1001047
GoogleScholar 82
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Other papers

2023-08 Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Lena R. Kaisinger, Katherine A. Kentistou, Stasa Stankovic, Eugene J. Gardner, Felix R. Day, Yajie Zhao,1 Alexander Mörseburg, Christopher J. Carnie, Guido Zagnoli-Vieira, Fabio Puddu, Stephen P. Jackson, Stephen O’Rahilly, I. Sadaf Farooqi, Laura Dearden, Lucas C. Pantaleão, Susan E. Ozanne, Ken K. Ong, 
and John R.B. Perry
Cell Genomics 3, 100362, 2023, DOI: https://doi.org/10.1016/j.xgen.2023.100362
GoogleScholar 1
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2012-01 RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks.
Yoshitami Hashimoto, Fabio Puddu, and Vincenzo Costanzo
Nature Structural and Molecular Biology, 2012, DOI:10.1038/nsmb.2177
GoogleScholar 185
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2009-09 Checkpoint mechanisms at the intersection between DNA damage and repair.
Federico Lazzaro, Michele Giannattasio,Fabio Puddu, Magda Granata, Achille Pellicioli, Paolo Plevani, and Marco Muzi-Falconi
DNA Repair (Amst), 2009, DOI: 10.1016/j.dnarep.2009.04
GoogleScholar 123
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